ISO 21439:2009 临床放射量测定 近距治疗用β放射源
标准编号：ISO 21439:2009
中文名称：临床放射量测定 近距治疗用β放射源
英文名称：Clinical dosimetry — Beta radiation sources for brachytherapy
发布日期：2009-02
标准范围
ISO 21439:2009规定了在眼科肿瘤和血管内近距离放射治疗中开始β射线应用程序之前，水或组织中吸收剂量分布的测定方法。本文给出了β辐射源校准、剂量测量、剂量计算、剂量测量质量保证以及β辐射近距离放射治疗计划的建议。还提供了估算水吸收剂量不确定度的指南。ISO 21439:2009适用于“密封”放射源，如平面和凹面放射源、单种子放射源系列、线放射源、壳放射源和体积放射源，对于这些放射源，只有发射的β辐射具有治疗相关性。ISO 21439:2009中描述的临床剂量测量程序的标准化是可靠应用β射线近距离治疗的基础。ISO 21439:2009中描述的特定剂量测定方法适用于眼科疾病的治疗、血管内近距离放射治疗、克服再狭窄问题以及使用β射线的其他临床应用。ISO 21439:2009适用于希望在剂量测定中建立参考方法的组织，旨在满足临床对交付剂量的适当小不确定度的要求。ISO 21439:2009不排除有其他方法导致相同或更小测量不确定度的可能性。
ISO 21439:2009 specifies methods for the determination of absorbed-dose distributions in water or tissue that are required prior to initiating procedures for the application of beta radiation in ophthalmic tumour and intravascular brachytherapy]. Recommendations are given for beta-radiation source calibration, dosemetry measurements, dose calculation, dosemetric quality assurance, as well as for beta-radiation brachytherapy treatment planning. Guidance is also given for estimating the uncertainty of the absorbed dose to water. ISO 21439:2009 is applicable to “sealed” radioactive sources, such as plane and concave surface sources, source trains of single seeds, line sources, shell and volume sources, for which only the beta radiation emitted is of therapeutic relevance.The standardization of procedures in clinical dosemetry described in ISO 21439:2009 serves as a basis for the reliable application of beta-radiation brachytherapy. The specific dosemetric methods described in ISO 21439:2009 apply to sources for the curative treatment of ophthalmic disease, for intravascular brachytherapy treatment, for overcoming the problem of restenosis and for other clinical applications using beta radiation.ISO 21439:2009 is geared towards organizations wishing to establish reference methods in dosemetry aiming at clinical demands for an appropriately small uncertainty of the delivered dose. ISO 21439:2009 does not exclude the possibility that there can be other methods leading to the same or smaller measurement uncertainties.
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