ISO/TS 19590:2017 纳米技术 大小分布和浓度的无机纳米粒子在水媒体通过单粒子电感耦合等离子体质谱法
标准编号：ISO/TS 19590:2017
中文名称：纳米技术 大小分布和浓度的无机纳米粒子在水媒体通过单粒子电感耦合等离子体质谱法
英文名称：Nanotechnologies — Size distribution and concentration of inorganic nanoparticles in aqueous media via single particle inductively coupled plasma mass spectrometry
发布日期：2017-03
标准范围
ISO/TS 19590:2017规定了一种用于检测水悬浮液中的纳米颗粒并表征颗粒数量和颗粒质量浓度以及基于数量的尺寸分布的方法，使用时间分辨模式的ICP-MS来确定单个纳米颗粒的质量和离子浓度。该方法适用于测定无机纳米颗粒（例如金属和金属氧化物，如Au、Ag、TiO2、BVO4等）的尺寸。），尺寸范围为10nm至100nm（以及高达1000nm至2000nm的较大颗粒）在水悬浮液中。如果化学组成和密度已知，则可以确定除氧化物以外的金属化合物(例如硫化物等)、金属复合材料或具有金属核的涂覆颗粒。可在水性悬浮液中测定的颗粒数浓度范围为106颗粒/L至109颗粒/L，其对应于约1ng/L至1000ng/L范围内的质量浓度（对于60nm Au颗粒).实际数字取决于所用质谱仪的类型和所分析的纳米颗粒的类型。除了颗粒浓度之外，还可以测定悬浮液中的离子浓度。检测限与标准ICP-MS测量相当。注意，具有小于spICP-MS方法的粒度检测极限的尺寸的纳米颗粒可以定量为离子。本文件中提出的方法不适用于有机或碳基纳米颗粒如胶囊、富勒烯和碳纳米管(CNT)的检测和表征。此外，它不适用于碳以外的难以用ICP-MS测定的元素。参考文献[5]概述了可以用spICP-MS检测的元素和可以确定的最小粒度。
ISO/TS 19590:2017 specifies a method for the detection of nanoparticles in aqueous suspensions and characterization of the particle number and particle mass concentration and the number-based size distribution using ICP-MS in a time-resolved mode to determine the mass of individual nanoparticles and ionic concentrations.The method is applicable for the determination of the size of inorganic nanoparticles (e.g. metal and metal oxides like Au, Ag, TiO2, BVO4, etc.), with size ranges of 10 nm to 100 nm (and larger particles up to 1 000 nm to 2 000 nm) in aqueous suspensions. Metal compounds other than oxides (e.g. sulfides, etc.), metal composites or coated particles with a metal core can be determined if the chemical composition and density are known. Particle number concentrations that can be determined in aqueous suspensions range from 106 particles/L to 109 particles/L which corresponds to mass concentrations in the range of approximately 1 ng/L to 1 000 ng/L (for 60 nm Au particles). Actual numbers depend on the type of mass spectrometer used and the type of nanoparticle analysed.In addition to the particle concentrations, ionic concentrations in the suspension can also be determined. Limits of detection are comparable with standard ICP-MS measurements. Note that nanoparticles with sizes smaller than the particle size detection limit of the spICP-MS method may be quantified as ionic.The method proposed in this document is not applicable for the detection and characterization of organic or carbon-based nanoparticles like encapsulates, fullerenes and carbon nanotubes (CNT). In addition, it is not applicable for elements other than carbon and that are difficult to determine with ICP-MS. Reference [5] gives an overview of elements that can be detected and the minimum particle sizes that can be determined with spICP-MS.
标准预览图
