ISO 23921:2020 卷烟 强吸烟状态下主流卷烟烟雾中烟草专用亚硝胺的测定 LC-MS/MS法

标准编号：ISO 23921:2020

中文名称：卷烟 强吸烟状态下主流卷烟烟雾中烟草专用亚硝胺的测定 LC-MS/MS法

英文名称：Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke with an intense smoking regime — Method using LC-MS/MS

发布日期：2020-09

标准范围

本文件规定了使用反相高效液相色谱-串联质谱法（LC-MS/MS）在ISO 20778规定的强烈吸烟条件下，对香烟主流烟雾总颗粒物中四种烟草特有亚硝胺（TSNAs）进行定量的方法。定量的TSNA包括:N-亚硝基鸟嘌呤（NNN）、N-亚硝基鸟嘌呤（NAT）、N-亚硝基鸟嘌呤（NAB）和4-（甲基亚硝胺）-1-（3-吡啶基）-1-丁酮（NNK）。

This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of cigarette mainstream smoke with the intense smoking regime specified in ISO 20778 by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

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